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(2) CCK-1R knockout rats exhibit a blunted response to peptone 190
doi: 10.1007/s00125-017-4318-z
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These larger, longer-duration studies will provide more definitive data on efficacy, durability of response, and the compounds broader metabolic profile
In OVX rat, administration of semaglutide at ~ 21 and 43 g/kg/day resulted in body weight loss in the animals, but also to improvement in BMD at the axial and appendicular skeleton associated with a reduction in BTMs [58]
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